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Recent evidence further supports this link, showing that NS workers had a significantly higher risk of testing positive for SARS-CoV-2 compared to DS workers, suggesting that circadian disruption and sleep loss may increase susceptibility to infectious diseases through impaired immune regulation 122

GPx4 is the membrane-associated enzyme which can specifically catalyze the reduction of complex lipid hydroperoxides by using GSH as a reducing equivalent and therefore is also known as phospholipid hydroperoxides [1, 8, 9]